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brandenbusch


Habicht J.; Brandenbusch C.; Sadowski G.:

Predicting PC-SAFT pure-component parameters by machine learning using a molecular fingerprint as key input

Fluid Phase Equilibria, vol. 565, p. 113657, 2023

https://doi.org/10.1016/j.fluid.2022.113657


Stolzke T.; Brandenbusch C.:

Simplified choice of suitable excipients within biologics formulation design using protein-protein interaction- and water activity-maps

European Journal of Pharmaceutics and Biopharmaceutics, vol. 176, pp. 153-167, 2022

https://doi.org/10.1016/j.ejpb.2022.05.017


Kroll P.; Benke J.; Enders S.; Brandenbusch C.; Sadowski G.:

Influence of Temperature and Concentration on the Self-Assembly of Nonionic CiEj Surfactants: A Light Scattering Study

ACS Omega, vol. 7, pp. 7057-7065, 2022

https://doi.org/10.1021/acsomega.1c06766


Kroll P.; Sadowski G.; Brandenbusch C.:

Solubilization of Aldehydes and Amines in Aqueous CiEj Surfactant Aggregates: Solubilization Capacity and Aggregate Properties

Langmuir, vol. 38, pp. 10022-10031, 2022

https://doi.org/10.1021/acs.langmuir.2c01463


Nolte L.; Nowaczyk M.; Brandenbusch C.:

Monitoring and investigating reactive extraction of (di–)carboxylic acids using online FTIR – Part I: Characterization of the complex formed between itaconic acid and tri-n-octylamine

Journal of Molecular Liquids, vol. 352, p. 118721, 2022

https://doi.org/10.1016/j.molliq.2022.118721


Nolte L.; Brandenbusch C.:

Monitoring and investigating reactive extraction of (di–)carboxylic acids using online FTIR – Part II: Reaction equilibria, reaction kinetics and competition within the complex formation between itaconic acid and several amine extractants

Journal of Molecular Liquids, vol. 366, p. 120223, 2022

https://doi.org/10.1016/j.molliq.2022.120223


Janssen L.; Sadowski G.; Brandenbusch C.:

Long-term stable bioprocess-derived Pickering-type emulsions: Identification of key parameters for emulsion stability based on cell interaction at interface

Chemical Engineering Science, vol. 264, p. 118164, 2022

https://doi.org/10.1016/j.ces.2022.118164


Wessner M.; Meier M.; Bommarius B.; Bommarius A.; Brandenbusch C.:

Intensifying aqueous two-phase extraction by adding decisive excipients for enhancement of stability and solubility of biomolecules

Chemical Engineering and Processing - Process Intensification, vol. 167, p. 108534, 2021

https://doi.org/10.1016/j.cep.2021.108534


Wessner M.; Bommarius B.; Brandenbusch C.; Bommarius A.:

Purification of chimeric amine dehydrogenase using a tailor-made aqueous two-phase system - A case study

Journal of Molecular Liquids, vol. 323, p. 114991, 2021

https://doi.org/10.1016/j.molliq.2020.114991


Prell C.; Busche T.; Rückert C.; Nolte L.; Brandenbusch C.; Wendisch V.:

Adaptive laboratory evolution accelerated glutarate production by Corynebacterium glutamicum

Microbial Cell Factories, vol. 20, p. 97, 2021

https://doi.org/10.1186/s12934-021-01586-3


Wessner M.; Nowaczyk M.; Brandenbusch C.:

Rapid identification of tailor-made aqueous two-phase systems for the extractive purification of high-value biomolecules

Journal of Molecular Liquids, vol. 314, p. 113655, 2020

https://doi.org/10.1016/j.molliq.2020.113655


Wessner M.; Diederich K.; Brandenbusch C.:

Influence of Sodium Chloride and Lithium Bromide on the Phase Behavior of a Citrate–Polyethylene Glycol 2000 Aqueous Two-Phase System

Journal of Chemical & Engineering Data, vol. 65, pp. 4009-4017, 2020

https://doi.org/10.1021/acs.jced.0c00319


Schleinitz M.; Nolte L.; Brandenbusch C.:

Predicting protein-protein interactions using the ePC-SAFT equation-of-state

Journal of Molecular Liquids, vol. 298, p. 112011, 2020

http://doi.org/10.1016/J.Molliq.2019.112011


Schleinitz M.; Sadowski G.; Brandenbusch C.:

Protein-protein interactions and water activity coefficients can be used to aid a first excipient choice in protein formulations

International Journal of Pharmaceutics, vol. 569, p. 118608, 2019

http://doi.org/10.1016/j.ijpharm.2019.118608


Schleinitz M.; Teschner D.; Sadowski G.; Brandenbusch C.:

Second osmotic virial coefficients of therapeutic proteins in the presence of excipient-mixtures can be predicted to aid an efficient formulation design

Journal of Molecular Liquids, vol. 283, pp. 575-583, 2019

https://doi.org/10.1016/j.molliq.2019.03.064


Wolbert F; Brandenbusch C; Sadowski G:

Selecting Excipients Forming Therapeutic Deep Eutectic Systems - A Mechanistic Approach

Molecular Pharmaceutics, vol. 16, pp. 3091-3099, 2019

https://doi.org/10.1021/acs.molpharmaceut.9b00336


Voges M.; Herhut M.; Held C.; Brandenbusch C.:

Light-scattering data of protein and polymer solutions: A new approach for model validation and parameter estimation

Fluid Phase Equilibria, vol. 465, pp. 65-72, 2018

https://doi.org/10.1016/j.fluid.2018.02.022


Gorden J.; Geiser E.; Wierckx N.; Blank L. M.; Zeiner T.; Brandenbusch C.:

Integrated process development of a reactive extraction concept for itaconic acid and application to a real fermentation broth

Engineering in Life Sciences, vol. 17, pp. 809-816, 2017

https://doi.org/10.1002/elsc.201600253


Kress C.; Sadowski G.; Brandenbusch C.:

Solubilization of proteins in aqueous two-phase extraction through combinations of phase-formers and displacement agents

European Journal of Pharmaceutics and Biopharmaceutics, vol. 112, pp. 38-44, 2017

https://doi.org/10.1016/j.ejpb.2016.11.016


Glonke S.; Sadowski G.; Brandenbusch C.:

Applied catastrophic phase inversion: a continuous non-centrifugal phase separation step in biphasic whole-cell biocatalysis

Journal of Industrial Microbiology & Biotechnology, vol. 43, pp. 1527-1535, 2016

https://doi.org/10.1007/s10295-016-1837-4


Herhut M.; Brandenbusch C.; Sadowski G.:

Modeling and prediction of protein solubility using the second osmotic virial coefficient

Fluid Phase Equilibria, vol. 422, pp. 32-42, 2016

https://doi.org/10.1016/j.fluid.2016.01.020


Herhut M.; Brandenbusch C.; Sadowski G.:

Non-monotonic course of protein solubility in aqueous polymer-salt solutions can be modeled using the sol-mxDLVO model

Biotechnology Journal, vol. 11, pp. 282-289, 2016

https://doi.org/10.1002/biot.201500123


Herhut M.; Brandenbusch C.; Sadowski G.:

Inclusion of mPRISM potential for polymer-induced protein interactions enables modeling of second osmotic virial coefficients in aqueous polymer-salt solutions

Biotechnology Journal, vol. 11, pp. 146-54, 2016

https://doi.org/10.1002/biot.201500086


Gorden J.; Zeiner T.; Sadowski G.; Brandenbusch C.:

Recovery of cis,cis-Muconic Acid from Organic Phase after Reactive Extraction

Separation and Purification Technology, vol. 169, pp. 1-8, 2016

https://doi.org/10.1016/j.seppur.2016.05.032


Kress C.; Sadowski G.; Brandenbusch C.:

Novel Displacement Agents for Aqueous 2-Phase Extraction Can Be Estimated Based on Hybrid Shortcut Calculations

Journal of Pharmaceutical Sciences, vol. 105, pp. 3030-3038, 2016

https://doi.org/10.1016/j.xphs.2016.06.006


Kress C.; Sadowski G.; Brandenbusch C.:

Protein partition coefficients can be estimated efficiently by hybrid shortcut calculations

Journal of Biotechnology, vol. 233, pp. 151-159, 2016

https://doi.org/10.1016/j.jbiotec.2016.06.032


Reschke T.; Brandenbusch C.; Sadowski G.:

Modeling aqueous two-phase systems: III. Polymers and organic salts as ATPS former

Fluid Phase Equilibria, vol. 387, pp. 178-189, 2015

https://doi.org/10.1016/j.fluid.2014.12.011


C. Kress; C. Brandenbusch:

Osmotic Virial Coefficients as Access to the Protein Partitioning in Aqueous Two-Phase Systems

Journal of Pharmaceutical Sciences, vol. 104, pp. 3703-3709, 2015

https://doi.org/10.1002/jps.24602


Gorden J.; Zeiner T.; Brandenbusch C.:

Reactive extraction of cis,cis-muconic acid

Fluid Phase Equilibria, vol. 393, pp. 78-84, 2015

https://doi.org/10.1016/j.fluid.2015.02.030


Collins J.; Grund M.; Brandenbusch C.; Sadowski G.; Schmid A.; Buhler B.:

The dynamic influence of cells on the formation of stable emulsions in organic-aqueous biotransformations

Journal of Industrial Microbiology & Biotechnology, vol. 42, pp. 1011-1026, 2015

https://doi.org/10.1007/s10295-015-1621-x


Kress C.; Brandenbusch C.:

Osmotic Virial Coefficients as Access to the Protein Partitioning in Aqueous Two-Phase Systems

Journal of Pharmaceutical Sciences, vol. 104, pp. 3703-3709, 2015

https://doi.org/10.1002/jps.24602


Brandenbusch C.; Glonke S.; Collins J.; Hoffrogge R.; Grunwald K.; Buhler B.; Schmid A.; Sadowski G.:

Process boundaries of irreversible scCO(2)-assisted phase separation in biphasic whole-cell biocatalysis

Biotechnology and Bioengineering, vol. 112, pp. 2316-2323, 2015

https://doi.org/10.1002/bit.25655


Reschke T.; Brandenbusch C.; Sadowski G.:

Modeling aqueous two-phase systems: II. Inorganic salts and polyether homo- and copolymers as ATPS former

Fluid Phase Equilibria, vol. 375, pp. 306-315, 2014

https://doi.org/10.1016/j.fluid.2014.04.040


Reschke T.; Brandenbusch C.; Sadowski G.:

Modeling aqueous two-phase systems: I. Polyethylene glycol and inorganic salts as ATPS former

Fluid Phase Equilibria, vol. 368, pp. 91-103, 2014

https://doi.org/10.1016/j.fluid.2014.02.016


Vogelpohl C.; Brandenbusch C.; Sadowski G.:

High-pressure gas solubility in multicomponent solvent systems for hydroformylation. Part II: Syngas solubility

The Journal of Supercritical Fluids, vol. 88, pp. 74-84, 2014

https://doi.org/10.1016/j.supflu.2014.01.017


Vogelpohl C.; Brandenbusch C.; Sadowski G.:

High-pressure gas solubility in multicomponent solvent systems for hydroformylation. Part I: Carbon monoxide solubility

Journal of Supercritical Fluids, vol. 81, pp. 23-32, 2013

https://doi.org/10.1016/j.supflu.2013.04.006


Ütkür F. Ö.; Tran T. T.; Collins J.; Brandenbusch C.; Sadowski G.; Schmid A.; Buhler B.:

Integrated organic-aqueous biocatalysis and product recovery for quinaldine hydroxylation catalyzed by living recombinant Pseudomonas putida

Journal of Industrial Microbiology & Biotechnology, vol. 39, pp. 1049-1059, 2012

https://doi.org/10.1007/s10295-012-1106-0


Ütkür F. Ö.; Thanh Tran T.; Collins J.; Brandenbusch C.; Sadowski G.; Schmid A.; Bühler B.:

Integrated organic–aqueous biocatalysis and product recovery for quinaldine hydroxylation catalyzed by living recombinant Pseudomonas putida KT2440 (pKP1)

Journal of Industrial Microbiology & Biotechnology, vol. 39, pp. 1049-1059, 2012

https://doi.org/10.1007/s10295-012-1106-0


Brandenbusch C.; Sadowski G.:

Supercritical phase behavior for biotransformation processing

Journal of Supercritical Fluids, vol. 55, pp. 635-642, 2010

https://doi.org/10.1016/j.supflu.2010.10.025


Brandenbusch C.; Bühler B.; Hoffmann P.; Sadowski G.; Schmid A.:

Efficient Phase Separation and Product Recovery in Organic-Aqueous Bioprocessing Using Supercritical Carbon Dioxide

Biotechnology and Bioengineering, vol. 107, pp. 642-651, 2010

https://doi.org/10.1002/bit.22846